Az értekezés címe az értekezés nyelvén Investigations of Pathological Conditions and Circulation during Oncological Reconstructive Surgeries Az értekezés címe magyarul Onkológiai helyreállító műtétek keringéspatológiai vizsgálatai Absztrakt az értekezés nyelvén Cancer has a major impact on society across the world.
Inan estimated The four most common cancers occurring worldwide are: lung, female breast, colorectal and prostate cancer.
These four account for around 4 in 10 of all cancers diagnosed worldwide.
The prostate cancer symptoms early diagnosis would be essential in all cases, to prevent further complications and the development of metastases. Unfortunately, in most of the cases, the specific symptoms occur only at the advanced stage, so the role of the screening programs and of the suitable tumour markers are high.
The importance of the tumour markers should be also emphasized in the postoperative period, for early detection or exclusion of the recurrence of the cancer or for the detection of a second tumour. There are a lot of attempt to find new markers, but still, it is very important to do researches on this field and improve the diagnostic tool for cancers.
Beside the early diagnosis and adequate therapy, reconstruction of the defects after oncological ablative surgeries is also a big challenge for the plastic-reconstructive surgeons. One optional procedure is the reconstruction with autologous tissues, when the own tissue of the body is used for reconstruction.
In these cases different flaps can be chosen: local flap, regional flap or free tissue transfer. Although, the success rates of free tissue transfer are high, there are still some cases, where the insufficient microcirculation, caused by ischemia-reperfusion injury IRIleads to partial flap loss and results in the reoperation of the patient.